Institute of Human Genetics, Montpellier
The postdoctoral researcher will investigate the molecular and epigenetic mechanisms underlying the transcriptional regulation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA),the viral reservoir responsible for persistent infection. By combining state-of-the-art approaches in molecular biology, virology, epigenetics, and single-molecule analysis, the project aims to uncover the mechanisms that regulate HBV transcription and contribute to the establishment and maintenance of viral persistence.
Centre d’Immunologie de Marseille-Luminy (CIML)
The primary mission of the appointee will be to conduct experimental research as part of an INCA PL-BIO project aimed at understanding the role of the endoplasmic reticulum unfolded protein response in potentiating immunotherapy treatments. Cell biology and immunology methodologies, including advanced cellular imaging, cytometry, molecular biology, and "omics" techniques, will be implemented to understand how small molecules that stimulate the UPR synergize with the innate immune response to enhance the efficacy of immunotherapeutic treatments.
Université de Caen Normandie
We are seeking a highly motivated postdoctoral researcher to join the MAGLAB Viral Evolution and Genetic Adaptation Group (Dr. Meriadeg Ar Gouilh) at UMR 1311 Inserm Dynamicure @ University of Caen Normandy. Our team investigates the emergence mechanisms and virus-host interactions of sarbecoviruses (coronaviruses) in bats.
IRD, Montpellier
UMR Intertryp (IRD/Cirad/Univ Montpellier) is a research unit dedicated to combating neglected tropical diseases (NTDs), in particular those caused by trypanosomatids, with the aim of improving human and animal health. Your mission will focus on the discovery of new drugs for Chagas disease.
Institut Pasteur de Lille
As part of an interdisciplinary project funded by the Priority Research Program and Equipment on Emerging Infectious Diseases (PEPR-MIE), we are seeking a motivated postdoctoral researcher to investigate the molecular mechanisms used by Yersinia pestis to infect fleas. The project will combine bacterial genetics, molecular microbiology, flea infection models and omics-based approaches to identify bacterial determinants required for colonisation, survival and transmission in the flea vector.
CIML - Centre d’Immunologie de Marseille-Luminy, Marseille
As part of the PEPR-MIE "UNFIRE" project, the postdoctoral researcher will investigate how plasmacytoid dendritic cells (pDCs) and various candidate modulators influence antiviral and inflammatory responses in a human airway epithelium (HAE) model infected with respiratory viruses. The project will be carried out within the Dendritic Cell Biology in CIML (Centre d’Immunologie de Marseille-Luminy), a multidisciplinary environment combining immunology, cellular virology, and systems biology.
Center of Structural Biology (INSERM), Montpellier
The project engineers probiotic Escherichia coli Nissle 1917 with a protective polymer coating and synthetic genetic circuits that trigger localised secretion of therapeutic single-domain antibodies at the tumour site, with the goal of establishing proof of concept for a programmable, targeted and tolerable lung cancer therapy.
PARis Cardiovascular research Center, Paris
The successful candidate will join the Kidney, Vessels, Inflammation and Metabolism (KVIM) team, which studies how immune, vascular,essels, Inflammation and Metabolism (KVIM) team, which studies how immune, vascular and metabolic pathways shape kidney injury and fibrosis. We investigate the cellular and molecular mechanisms that drive human kidney diseases, from early injury to organ failure.
Centre d'Immunologie de Marseille-Luminy, Marseille
The successful candidate will lead an innovative research project funded by the Impulscience Grant from the Bettencourt-Schueller Foundation. The project aims to investigate how sensory neurons regulate immune cell function during inflammation, using both mouse models and human cellular systems. This work is expected to uncover fundamental neuro-immune mechanisms and may open new therapeutic avenues for inflammatory diseases.
Institut Pasteur, Paris
We are seeking an outstanding postdoctoral researcher with a strong background in bacterial genomics and evolutionary biology to join an ambitious project that will reconstruct the twentieth-century global evolution of Salmonella enterica serotype Typhi (S. Typhi), the human-restricted pathogen causing typhoid fever. This project offers a rare opportunity to work on a unique historical genomic resource and to answer fundamental questions in pathogen evolution by reconnecting classical epidemiology with modern bacterial genomics.